Though Britain's policy of salutary neglect before 1750 influenced the development of America's legislative assemblies, its commerce, and religion, those three aspects were affected differently. Salutary neglect created diverse commerce in America through the Triangular Trade, which contributed to the shipments of smuggled goods. Three individuals, Jacobus Arminians, John Edwards, and George Whitefield, supported the Great Awakening, which causes major changes in religion due to salutary neglect. The legislative assemblies that were mainly affected from salutary neglect were the new ideas of creating different parliaments with the increased amounts of political freedom, and the new ideas of self-governing, which was cherished above other rights by many Americans. Commerce in America was greatly altered from salutary neglect. The Triangular Trade originally was a trade strictly consisting of 3 parts; from North America, ships carrying rum were transported to Africa in return for slaves.

With the slaves bundled up in tight quarters on ships, they would sail back to the colonies or to the French West Indies, where sugar and molasses could be traded for the slaves. The sugar and molasses would now go back to the colonies, to be manufactured into rum to be sent out to Africa again. Smugglers had a hard time of taking their goods that were not approved by an English official.

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But since salutary neglect was "in effect", the Navigation Acts were not being enforced as heavily as it has been. Also, ignoring the mercantilism restrictions on the colonies would have not been a good idea if it had not been for salutary neglect. Outgoing ships had the ability to go to other countries and continents such as the French West Indies without getting caught and be heftily fined or have their goods taken away. Officials were becoming less-competent and more bribe-effective. They would do a less than sufficient job of keeping an eye.