Sleep and blood, two very different things, but carry the same amount of significant throughout William Shakespeare’s; The Tragedy of Macbeth. Blood was used many times throughout William Shakespeare’s; The Tragedy of Macbeth and it was used to represent many things whether it would be foreshadowing, the representation of an individual’s position or consequences an action the character has taken. The one of the first time blood is introduced is in this line “And on thy blade and dungeon, gouts of blood, which was not so before. There’s no such thing: it is the bloody business which informs thus to mine eyes.” The imagery used here to portray blood represents his ambitions to betray Duncan and kill him for the crown but this could also portray the guilt inside Macbeth and how he regrets his actions. Blood is used many more times to show how Macbeth feels guilty examples of this is when Macbeth has blood on his hands after he murdered King Duncan and he says “Will all great Neptune’s ocean wash this blood clean from my hand?” this refers to him saying will all the water in the ocean clean my bloody hands meaning will all my efforts take this murder off my hands. Another time blood is used to portray guilt is when Macbeth sees Banquo’s ghost and the ghost is ordering people to kill Macbeth, this just shows how Macbeth’s guilty mindset had taken him over. From these examples, we can see the blood is a key factor in Macbeth’s guilt and it shows how he lost a grip on reality due to all the blood he had on his hands and the guilt of it.Sleep is also a huge factor throughout William Shakespeare’s; The Tragedy of Macbeth. When he murdered Duncan while Duncan was sleeping he didn’t just murder Duncan he murdered his own sleep. Sleep represents the idea of guilt and how guilt kills sleep. In Act 5 Scene 1 you can clearly see that Lady Macbeth’s guilty conscience is killing her slowly, “I have seen her rise from her bed, throw her nightgown upon her, unlock her closet, take forth paper, fold it, write upon’t , read it, afterwards seal it, and again return to bed; yet all this while in a most fast sleep.” this shows that Lady Macbeth cannot sleep properly while sleeping, and this foreshadows her death. Sleep had such an important significance in the text, sleep is a state where one with a clear and peaceful mind shall rest and Macbeth and Lady Macbeth’s troubles sleeping peacefully just show how guilty their conscience was. Blood and sleep were prominent factors in this story and helped  William Shakespeare’s; The Tragedy of Macbeth become the classic it is today.