Cervical Disc is one of the more vitally important andmechanically astounding skeletal structures, which allows a vast range ofmotion between the vertebrae in the neck, all the while absorbing large amountsof compression from regular movement.

This paper presents a comprehensivereview and critical comparison of most recent design and optimization methodsof cervical disc. In order to solve an optimization problem of an artificialdisc, various assessment parameters such as load, material and it is propertiesand geometry are explained and summarized. The selection of some of theseparameters is essentially to obtain an optimal combination for the artificialdisc. Based on the review, it is observed that the use of experimental resultsand validate data in the optimization problem improve the results compared tothe use of analytical solution only, but unfortunately a few author usedoptimization algorithms, as it is mention in tables (6 and 9). Most of thepapers for CD system are carried out based on finite element analysis includingselection of type of element, number of element and mechanical properties.However, as a natural geometry, ROM and natural material are considering as themost important constrains, there is a need for even much accurate and highlyadvanced optimization for selecting of artificial disc replacement. Therefore,to solve the complexity of this mechanism a hybrid algorithms and moreoptimization algorithms with robust controller need to be apply for CDproblems. Moreover, software computer tools are also used widely for designingof artificial CD.

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However, using modern technique, material and methods willprovide more accurate optimization results than the regular software and theold tools as they have the ability to solve multi-objective optimizationproblems. This paper reviews the main basic research methods and theircorresponding applications in CD, aiming to let more experts know the currentresearch status and also provide some guidance for relevant researches. Basedon previous studies FE method is the most appropriate to follow. Moreover, onthe proposed study the objective will be, to design and analysis a CD.